{"id":"doi:10.1161/circulationaha.122.062132","kind":"article","title":"Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting PCSK9 in Nonhuman Primate and Mouse Models","authors":["Richard G. Lee","Anne Marie Mazzola","Maurine C. Braun","Colin Platt","Scott B. Vafai","Sekar Kathiresan","Ellen Rohde","Andrew M. Bellinger","Amit V. Khera"],"author_count":9,"year":2022,"published":"2022-10-31","venue":"Circulation","cited_by":243,"doi":"10.1161/circulationaha.122.062132","arxiv_id":null,"nct_id":null,"source_url":"https://doi.org/10.1161/circulationaha.122.062132","archive_url":"https://space-kitty.com/papers/doi:10.1161/circulationaha.122.062132","updated":null,"pmid":"36314243","pmcid":null,"openalex_id":"W4307777231","pdf_url":null,"abstract":null,"abstract_license":null,"license":null,"is_open_access":false,"retracted":false,"peer_reviewed":null,"categories":["CRISPR and Genetic Engineering"],"details":null,"provenance":"openalex","attribution":"Metadata and citation counts: OpenAlex (CC0).","topics":[{"slug":"gene-editing-therapies","name":"CRISPR & Gene-Editing Therapies","domain_slug":"medicine"}],"cited_in_dossiers":[]}