{"id":"nct:NCT00003641","kind":"trial","title":"High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma","authors":["ECOG-ACRIN Cancer Research Group"],"author_count":1,"year":2003,"published":"2003-01-27","venue":"ClinicalTrials.gov","cited_by":null,"doi":null,"arxiv_id":null,"nct_id":"NCT00003641","source_url":"https://clinicaltrials.gov/study/NCT00003641","archive_url":"https://space-kitty.com/papers/nct:NCT00003641","updated":"2026-09-29","pmid":null,"pmcid":null,"openalex_id":null,"pdf_url":null,"abstract":"RATIONALE: Interferon alfa may interfere with the growth of cancer cells. It is not yet known whether treatment with interferon alfa is more effective than observation alone for stage II or stage III melanoma that has been completely removed surgically. PURPOSE: This randomized phase III trial is studying high dose interferon alfa to see how well it works compared to observation only in treating patients with stage II or stage III melanoma that has been completely removed by surgery.","abstract_license":"ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters","license":"ClinicalTrials.gov terms (attribution, processing date, modifications noted)","is_open_access":true,"retracted":false,"peer_reviewed":null,"categories":["Melanoma (Skin)"],"details":{"acronym":null,"status":"COMPLETED","phase":"PHASE3","study_type":"INTERVENTIONAL","enrollment":1150,"sponsor":"ECOG-ACRIN Cancer Research Group","conditions":["Melanoma (Skin)"],"interventions":["BIOLOGICAL: interferon alfa-2b","OTHER: observation"],"start_date":"1999-03-25","start_date_type":"ACTUAL","primary_completion_date":"2015-01-01","has_results":true,"data_source":"ClinicalTrials.gov","data_processed":"2026-10-29T09:00:05","modifications":"selected fields only; whitespace normalized; brief summary truncated to 2,000 characters"},"provenance":"clinicaltrials","attribution":"Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.","topics":[{"slug":"gene-cell-therapy","name":"Gene & Cell Therapy","domain_slug":"medicine"}],"cited_in_dossiers":[]}