{"id":"nct:NCT00007189","kind":"trial","title":"Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT)","authors":["Seattle Institute for Biomedical and Clinical Research"],"author_count":1,"year":2000,"published":"2000-12-14","venue":"ClinicalTrials.gov","cited_by":null,"doi":null,"arxiv_id":null,"nct_id":"NCT00007189","source_url":"https://clinicaltrials.gov/study/NCT00007189","archive_url":"https://space-kitty.com/papers/nct:NCT00007189","updated":"2016-10-19","pmid":null,"pmcid":null,"openalex_id":null,"pdf_url":null,"abstract":"The purpose of this trial is to test the ability of the non-steroidal anti-inflammatory medications naproxen and celecoxib to delay or prevent the onset of AD and age-related cognitive decline.","abstract_license":"ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters","license":"ClinicalTrials.gov terms (attribution, processing date, modifications noted)","is_open_access":true,"peer_reviewed":null,"categories":["Alzheimer Disease"],"details":{"acronym":null,"status":"COMPLETED","phase":"PHASE3","study_type":"INTERVENTIONAL","enrollment":2625,"sponsor":"Seattle Institute for Biomedical and Clinical Research","conditions":["Alzheimer Disease"],"interventions":["DRUG: Naproxen Sodium (Aleve)","DRUG: Celecoxib (Celebrex)"],"start_date":"2001-01-01","start_date_type":null,"primary_completion_date":"2007-05-01","has_results":false,"data_source":"ClinicalTrials.gov","data_processed":"2026-10-29T09:00:05","modifications":"selected fields only; whitespace normalized; brief summary truncated to 2,000 characters"},"provenance":"clinicaltrials","attribution":"Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.","topics":[{"slug":"neurodegeneration","name":"Alzheimer's, Parkinson's & Neurodegeneration","domain_slug":"medicine"}],"cited_in_dossiers":[]}