{"id":"nct:NCT04023552","kind":"trial","title":"Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD","authors":["Novartis Pharmaceuticals"],"author_count":1,"year":2019,"published":"2019-07-17","venue":"ClinicalTrials.gov","cited_by":null,"doi":null,"arxiv_id":null,"nct_id":"NCT04023552","source_url":"https://clinicaltrials.gov/study/NCT04023552","archive_url":"https://space-kitty.com/papers/nct:NCT04023552","updated":"2026-08-28","pmid":null,"pmcid":null,"openalex_id":null,"pdf_url":null,"abstract":"This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)","abstract_license":"ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters","license":"ClinicalTrials.gov terms (attribution, processing date, modifications noted)","is_open_access":true,"peer_reviewed":null,"categories":["Cardiovascular Disease and Lipoprotein(a)"],"details":{"acronym":"Lp(a)HORIZON","status":"COMPLETED","phase":"PHASE3","study_type":"INTERVENTIONAL","enrollment":8323,"sponsor":"Novartis Pharmaceuticals","conditions":["Cardiovascular Disease and Lipoprotein(a)"],"interventions":["DRUG: TQJ230","DRUG: Placebo"],"start_date":"2019-12-12","start_date_type":"ACTUAL","primary_completion_date":"2026-07-16","has_results":false,"data_source":"ClinicalTrials.gov","data_processed":"2026-10-29T09:00:05","modifications":"selected fields only; whitespace normalized; brief summary truncated to 2,000 characters"},"provenance":"clinicaltrials","attribution":"Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.","topics":[{"slug":"cardiovascular-innovation","name":"Cardiovascular Therapeutics","domain_slug":"medicine"}],"cited_in_dossiers":[]}