{"id":"nct:NCT05711940","kind":"trial","title":"Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD","authors":["COMPASS Pathways"],"author_count":1,"year":2023,"published":"2023-02-03","venue":"ClinicalTrials.gov","cited_by":null,"doi":null,"arxiv_id":null,"nct_id":"NCT05711940","source_url":"https://clinicaltrials.gov/study/NCT05711940","archive_url":"https://space-kitty.com/papers/nct:NCT05711940","updated":"2026-08-10","pmid":null,"pmcid":null,"openalex_id":null,"pdf_url":null,"abstract":"Efficacy, Safety, and Tolerability of two administrations of COMP360 in participants with treatment-resistant depression (TRD)","abstract_license":"ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters","license":"ClinicalTrials.gov terms (attribution, processing date, modifications noted)","is_open_access":true,"retracted":false,"peer_reviewed":null,"categories":["Treatment Resistant Depression"],"details":{"acronym":null,"status":"ACTIVE_NOT_RECRUITING","phase":"PHASE3","study_type":"INTERVENTIONAL","enrollment":572,"sponsor":"COMPASS Pathways","conditions":["Treatment Resistant Depression"],"interventions":["DRUG: Psilocybin"],"start_date":"2023-02-14","start_date_type":"ACTUAL","primary_completion_date":"2025-11-13","has_results":false,"data_source":"ClinicalTrials.gov","data_processed":"2026-10-29T09:00:05","modifications":"selected fields only; whitespace normalized; brief summary truncated to 2,000 characters"},"provenance":"clinicaltrials","attribution":"Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.","topics":[{"slug":"psychiatric-therapeutics","name":"Novel Psychiatric Therapeutics","domain_slug":"neuroscience"}],"cited_in_dossiers":[]}