{"id":"nct:NCT05882045","kind":"trial","title":"A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease","authors":["Eli Lilly and Company"],"author_count":1,"year":2023,"published":"2023-05-31","venue":"ClinicalTrials.gov","cited_by":null,"doi":null,"arxiv_id":null,"nct_id":"NCT05882045","source_url":"https://clinicaltrials.gov/study/NCT05882045","archive_url":"https://space-kitty.com/papers/nct:NCT05882045","updated":"2026-07-30","pmid":null,"pmcid":null,"openalex_id":null,"pdf_url":null,"abstract":"The main purpose of this study is to evaluate the efficacy and safety of retatrutide once weekly in participants with obesity and established cardiovascular disease (CVD). The study will last about 113 weeks.","abstract_license":"ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters","license":"ClinicalTrials.gov terms (attribution, processing date, modifications noted)","is_open_access":true,"retracted":false,"peer_reviewed":null,"categories":["Obesity","Cardiovascular Diseases"],"details":{"acronym":"TRIUMPH-3","status":"COMPLETED","phase":"PHASE3","study_type":"INTERVENTIONAL","enrollment":1946,"sponsor":"Eli Lilly and Company","conditions":["Obesity","Cardiovascular Diseases"],"interventions":["DRUG: Retatrutide","DRUG: Placebo"],"start_date":"2023-05-30","start_date_type":"ACTUAL","primary_completion_date":"2026-04-16","has_results":false,"data_source":"ClinicalTrials.gov","data_processed":"2026-10-29T09:00:05","modifications":"selected fields only; whitespace normalized; brief summary truncated to 2,000 characters"},"provenance":"clinicaltrials","attribution":"Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.","topics":[{"slug":"glp1-metabolic","name":"GLP-1 & Incretin Therapies","domain_slug":"medicine"}],"cited_in_dossiers":[{"slug":"glp1-metabolic","title":"GLP-1 & Incretin Therapies: State of the Field (October 2026)","url":"https://space-kitty.com/dossiers/glp1-metabolic"}]}