{"id":"nct:NCT06488794","kind":"trial","title":"Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia","authors":["University Hospital Fattouma Bourguiba"],"author_count":1,"year":2024,"published":"2024-07-05","venue":"ClinicalTrials.gov","cited_by":null,"doi":null,"arxiv_id":null,"nct_id":"NCT06488794","source_url":"https://clinicaltrials.gov/study/NCT06488794","archive_url":"https://space-kitty.com/papers/nct:NCT06488794","updated":"2026-10-08","pmid":null,"pmcid":null,"openalex_id":null,"pdf_url":null,"abstract":"The goal of this clinical trial is to learn if nebulized colistimethate sodium can prevent pneumonia in ventilated children. The main question it aims to answer is: • Does nebulized colistimethate sodium lower the number of times participants develop ventilation associated pneumonia? Researchers will compare nebulized colistimethate sodium to a placebo (a look-alike substance that contains no drug) to see if nebulized colistin works to prevent ventilation associated pneumonia in children. Participants will: * Take nebulized colistimethate sodium or a placebo twice a day for a maximum of 5 days. * Will be followed to check for pneumonia occurrence while they are on mechanical ventilation.","abstract_license":"ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters","license":"ClinicalTrials.gov terms (attribution, processing date, modifications noted)","is_open_access":true,"retracted":false,"peer_reviewed":null,"categories":["Ventilator Associated Pneumonia"],"details":{"acronym":"ColiPed","status":"NOT_YET_RECRUITING","phase":"PHASE2, PHASE3","study_type":"INTERVENTIONAL","enrollment":400,"sponsor":"University Hospital Fattouma Bourguiba","conditions":["Ventilator Associated Pneumonia"],"interventions":["DRUG: colistimethate sodium","DRUG: 0.9% Saline"],"start_date":"2027-01-01","start_date_type":"ESTIMATED","primary_completion_date":"2028-12-31","has_results":false,"data_source":"ClinicalTrials.gov","data_processed":"2026-10-29T09:00:05","modifications":"selected fields only; whitespace normalized; brief summary truncated to 2,000 characters"},"provenance":"clinicaltrials","attribution":"Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.","topics":[{"slug":"infectious-disease-amr","name":"Infectious Disease, Vaccines & Antimicrobial Resistance","domain_slug":"medicine"}],"cited_in_dossiers":[]}