{"id":"nct:NCT06605105","kind":"trial","title":"Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)","authors":["Cybin IRL Limited"],"author_count":1,"year":2024,"published":"2024-09-20","venue":"ClinicalTrials.gov","cited_by":null,"doi":null,"arxiv_id":null,"nct_id":"NCT06605105","source_url":"https://clinicaltrials.gov/study/NCT06605105","archive_url":"https://space-kitty.com/papers/nct:NCT06605105","updated":"2026-09-25","pmid":null,"pmcid":null,"openalex_id":null,"pdf_url":null,"abstract":"This is a long- term extension of the double-blind trials APPROACH (CYB003-002) and EMBRACE (CYB003-003). Its aim is to examine the safety and long-term efficacy of CYB003 in participants with MDD.","abstract_license":"ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters","license":"ClinicalTrials.gov terms (attribution, processing date, modifications noted)","is_open_access":true,"retracted":false,"peer_reviewed":null,"categories":["Major Depressive Disorder"],"details":{"acronym":"EXTEND","status":"ENROLLING_BY_INVITATION","phase":"PHASE3","study_type":"INTERVENTIONAL","enrollment":468,"sponsor":"Cybin IRL Limited","conditions":["Major Depressive Disorder"],"interventions":["DRUG: CYB003"],"start_date":"2025-07-18","start_date_type":"ACTUAL","primary_completion_date":"2028-06-06","has_results":false,"data_source":"ClinicalTrials.gov","data_processed":"2026-10-29T09:00:05","modifications":"selected fields only; whitespace normalized; brief summary truncated to 2,000 characters"},"provenance":"clinicaltrials","attribution":"Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.","topics":[{"slug":"psychiatric-therapeutics","name":"Novel Psychiatric Therapeutics","domain_slug":"neuroscience"}],"cited_in_dossiers":[]}