{"id":"nct:NCT07284979","kind":"trial","title":"Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes","authors":["Kailera"],"author_count":1,"year":2025,"published":"2025-12-16","venue":"ClinicalTrials.gov","cited_by":null,"doi":null,"arxiv_id":null,"nct_id":"NCT07284979","source_url":"https://clinicaltrials.gov/study/NCT07284979","archive_url":"https://space-kitty.com/papers/nct:NCT07284979","updated":"2026-10-06","pmid":null,"pmcid":null,"openalex_id":null,"pdf_url":null,"abstract":"The primary objective of this study is to demonstrate that ribupatide (KAI-9531) subcutaneous (SC) injection once weekly is superior to semaglutide SC once weekly and to placebo SC once weekly on percent change in body weight.","abstract_license":"ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters","license":"ClinicalTrials.gov terms (attribution, processing date, modifications noted)","is_open_access":true,"retracted":false,"peer_reviewed":null,"categories":["Obesity"],"details":{"acronym":"KaiNETIC-3","status":"ACTIVE_NOT_RECRUITING","phase":"PHASE3","study_type":"INTERVENTIONAL","enrollment":1270,"sponsor":"Kailera","conditions":["Obesity"],"interventions":["DRUG: Ribupatide","DRUG: Semaglutide","DRUG: Placebo"],"start_date":"2025-12-30","start_date_type":"ACTUAL","primary_completion_date":"2028-03-01","has_results":false,"data_source":"ClinicalTrials.gov","data_processed":"2026-10-29T09:00:05","modifications":"selected fields only; whitespace normalized; brief summary truncated to 2,000 characters"},"provenance":"clinicaltrials","attribution":"Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.","topics":[{"slug":"glp1-metabolic","name":"GLP-1 & Incretin Therapies","domain_slug":"medicine"}],"cited_in_dossiers":[]}