{"id":"nct:NCT07796308","kind":"trial","title":"Terazosin And Metabolic Engagement in Alzheimer's Disease","authors":["Qiang Zhang"],"author_count":1,"year":2026,"published":"2026-09-01","venue":"ClinicalTrials.gov","cited_by":null,"doi":null,"arxiv_id":null,"nct_id":"NCT07796308","source_url":"https://clinicaltrials.gov/study/NCT07796308","archive_url":"https://space-kitty.com/papers/nct:NCT07796308","updated":"2026-09-01","pmid":null,"pmcid":null,"openalex_id":null,"pdf_url":null,"abstract":"The TAME-AD trial will be a randomized, double-blind, placebo-controlled Phase IIa clinical trial to evaluate the metabolic target engagement of terazosin for the treatment of Alzheimer's disease.","abstract_license":"ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters","license":"ClinicalTrials.gov terms (attribution, processing date, modifications noted)","is_open_access":true,"retracted":false,"peer_reviewed":null,"categories":["Alzheimer s Disease"],"details":{"acronym":"TAME-AD","status":"NOT_YET_RECRUITING","phase":"PHASE2","study_type":"INTERVENTIONAL","enrollment":100,"sponsor":"Qiang Zhang","conditions":["Alzheimer s Disease"],"interventions":["DRUG: Terazosin (Hytrin)","OTHER: Placebo"],"start_date":"2027-08-01","start_date_type":"ESTIMATED","primary_completion_date":"2031-07-31","has_results":false,"data_source":"ClinicalTrials.gov","data_processed":"2026-10-29T09:00:05","modifications":"selected fields only; whitespace normalized; brief summary truncated to 2,000 characters"},"provenance":"clinicaltrials","attribution":"Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.","topics":[{"slug":"neurodegeneration","name":"Alzheimer's, Parkinson's & Neurodegeneration","domain_slug":"medicine"}],"cited_in_dossiers":[]}