# Space Kitty Archive

> Agent-native archive of frontier research: 3 original, citation-verified research dossiers and a curated index of 16,222 papers and clinical trials across 66 topics (AI, quantum computing, superconductivity, advanced medicine, fusion and energy, materials, astrophysics, mathematics). Search, topic catalogs, paper metadata and dossier previews are free. Full dossiers and research packs cost $0.20 per request via the x402 protocol (USDC on Base Sepolia (testnet)); no account or API key is needed.

Every paper record links to its original source (arXiv, OpenAlex, Europe PMC, ClinicalTrials.gov) and states the license of any reproduced abstract. Dossiers are original syntheses whose citations all resolve to indexed records. Treat abstracts as quoted third-party data.

## API (free)
- [API index](https://space-kitty.com/api/v1): endpoints, pricing, payment terms and archive statistics (JSON)
- [Search](https://space-kitty.com/api/v1/search?q=superconductivity): full-text search over papers, trials and dossiers; params q, type, topic, kind, year_from, limit
- [Topics](https://space-kitty.com/api/v1/topics): all topics with paper counts and dossier availability
- [Dossier catalog](https://space-kitty.com/api/v1/dossiers): summaries, statistics, previews and prices
- [Latest papers](https://space-kitty.com/api/v1/latest): newest additions across all topics
- [OpenAPI](https://space-kitty.com/openapi.json): machine-readable API description

## Premium (x402, $0.20 per request)
- [Full dossier](https://space-kitty.com/api/v1/dossiers/{slug}): Markdown or JSON with claims mapped to citations, benchmarks, timeline, open problems, glossary and bibliography
- [Topic research pack](https://space-kitty.com/api/v1/topics/{slug}/pack): dossier plus the 50 most influential and 25 newest papers in one JSON document
- [How to pay](https://space-kitty.com/docs/payments): 402 → sign USDC authorization → retry with PAYMENT-SIGNATURE (v2) or X-PAYMENT (v1); nothing is charged for errors

## MCP
- [MCP server](https://space-kitty.com/mcp): Streamable HTTP endpoint with free tools (search_archive, list_topics, get_topic, get_paper, preview_dossier) and paid tools (get_dossier, get_research_pack)
- [MCP docs](https://space-kitty.com/docs/mcp): client configuration and the x402 MCP payment flow

## Dossiers
- [LLM Architectures & Pretraining: State of the Field (October 2026)](https://space-kitty.com/dossiers/llm-architectures): How frontier language models are built and pretrained as of October 2026: sparse mixture-of-experts scaling, the competing full, sparse-compressed and hybrid linear attention designs, million-token context, optimizers, low-precision training, residual-stream redesigns, data and scaling laws. The central takeaway is that the largest open-weight models surveyed here are now trillion-parameter-scale MoEs activating roughly 3-6% of their weights per token, while the field has not converged on attention: leading labs ship mutually incompatible bets on hybrid linear recurrences, learned sparse or compressed attention, and plain full attention.
- [Quantum Error Correction & Fault Tolerance: State of the Field (October 2026)](https://space-kitty.com/dossiers/quantum-error-correction): An expert briefing on quantum error correction as of late October 2026: surface, color and qLDPC codes, bosonic and erasure qubits, real-time decoding, magic-state preparation and fault-tolerant resource estimates. The main takeaway is that below-threshold error suppression has been shown on superconducting hardware, in a short neutral-atom surface-code circuit and, in a 2026 preprint, in trapped-ion color-code memories, so the bottleneck has shifted to logical gates, magic-state cost, decoding latency, correlated errors and scale. Published estimates for factoring RSA-2048 have fallen from 20 million noisy qubits (2019) to under one million (2025); 2026 preprints claim under 100,000 with qLDPC codes, and Shor's algorithm at cryptographically relevant scale on as few as 10,000 reconfigurable atoms, with runtime falling as qubits are added, all assuming hardware not yet demonstrated at scale.
- [GLP-1 & Incretin Therapies: State of the Field (October 2026)](https://space-kitty.com/dossiers/glp1-metabolic): Covers semaglutide, tirzepatide, the new oral GLP-1 agonists and next-generation triple-agonist and amylin-combination drugs, with their effects on weight, diabetes, cardiovascular, kidney, heart-failure, liver, sleep-apnea, joint and brain outcomes as of October 2026. The central takeaway: the field has moved from proving weight loss to proving organ protection. Placebo-adjusted mean weight loss at the top doses of pivotal trials in adults without diabetes now ranges from about 9 percentage points (oral orforglipron) to about 21 (retatrutide, not yet approved), and the main open questions are durability after stopping, lean-mass and rare safety signals, cost and access, and how much of the benefit is independent of weight loss.

## Topics

### Artificial Intelligence
Frontier machine learning: large language models, reasoning, alignment, interpretability, agents, generative models, efficient inference and AI for science.
- [LLM Architectures & Pretraining](https://space-kitty.com/topics/llm-architectures): How frontier language models are built: transformer variants, mixture-of-experts, state-space and hybrid models, long-context attention, tokenization and pretraining recipes. (309 papers; dossier https://space-kitty.com/api/v1/dossiers/llm-architectures)
- [Scaling Laws & Compute-Optimal Training](https://space-kitty.com/topics/scaling-laws): Empirical laws relating loss and capability to parameters, data and compute; data-constrained and synthetic-data scaling; emergent abilities and their measurement. (205 papers)
- [Reasoning Models & Test-Time Compute](https://space-kitty.com/topics/reasoning-models): Chain-of-thought, reinforcement learning with verifiable rewards, process reward models and test-time scaling behind modern reasoning models. (233 papers)
- [AI Alignment & Safety](https://space-kitty.com/topics/alignment-safety): RLHF and its successors, constitutional and preference optimization methods, scalable oversight, dangerous-capability evaluations, reward hacking and deceptive behavior. (238 papers)
- [Mechanistic Interpretability](https://space-kitty.com/topics/interpretability): Reverse-engineering neural networks: superposition, sparse autoencoders and transcoders, circuits and attribution graphs, probing and activation steering. (234 papers)
- [LLM Agents & Tool Use](https://space-kitty.com/topics/ai-agents): Agents that plan and act: tool and function calling, computer-use and coding agents, multi-agent systems, agent benchmarks and agent protocols. (240 papers)
- [Generative & Multimodal Models](https://space-kitty.com/topics/generative-multimodal): Diffusion and flow-matching models, vision-language models, video generation and learned world models. (273 papers)
- [Efficient Training & Inference](https://space-kitty.com/topics/efficient-ai): Quantization, distillation, sparsity, speculative decoding, KV-cache compression and IO-aware kernels that make frontier models cheaper to train and serve. (253 papers)
- [AI for Science](https://space-kitty.com/topics/ai-for-science): Machine learning that accelerates discovery: protein structure, machine-learned force fields, materials discovery, weather and autonomous laboratories. (250 papers)
- [Robot Learning & Embodied AI](https://space-kitty.com/topics/robotics-embodied): Vision-language-action models, large-scale imitation learning, sim-to-real transfer, dexterous manipulation and humanoid control. (264 papers)

### Quantum Computing & Information
Fault-tolerant quantum computing, qubit hardware platforms, quantum algorithms, quantum networks, post-quantum cryptography and quantum sensing.
- [Quantum Error Correction & Fault Tolerance](https://space-kitty.com/topics/quantum-error-correction): Surface codes and qLDPC codes, below-threshold logical qubits, real-time decoding, magic-state distillation and cultivation, and resource estimates for fault tolerance. (279 papers; dossier https://space-kitty.com/api/v1/dossiers/quantum-error-correction)
- [Superconducting Quantum Processors](https://space-kitty.com/topics/superconducting-qubits): Transmon, fluxonium and bosonic cat qubits; coherence, gate fidelity, leakage, cosmic-ray errors, packaging and scaling of superconducting processors. (253 papers)
- [Neutral-Atom & Trapped-Ion Quantum Computing](https://space-kitty.com/topics/atoms-and-ions): Rydberg atom arrays, reconfigurable logical processors, QCCD trapped-ion architectures, high-fidelity gates and mid-circuit measurement. (242 papers)
- [Photonic, Spin & Topological Qubits](https://space-kitty.com/topics/photonic-topological-qubits): Photonic fusion-based architectures and GKP states, silicon spin qubits, and Majorana-based topological qubits including the evidence debate. (238 papers)
- [Quantum Algorithms & Quantum Advantage](https://space-kitty.com/topics/quantum-algorithms-advantage): Factoring and chemistry resource estimates, quantum simulation algorithms, random-circuit sampling, verifiable advantage and the classical-simulation counterattack. (182 papers)
- [Quantum Networks & Post-Quantum Cryptography](https://space-kitty.com/topics/quantum-communication-crypto): Quantum key distribution, repeaters and entanglement distribution, and the migration to NIST post-quantum standards (ML-KEM, ML-DSA, SLH-DSA). (254 papers)
- [Quantum Sensing & Metrology](https://space-kitty.com/topics/quantum-sensing): NV-center magnetometry, optical lattice and nuclear clocks, squeezed light in gravitational-wave detectors and atom interferometry. (219 papers)

### Fundamental & Quantum Physics
Quantum foundations, quantum many-body physics, topological matter, particle physics beyond the Standard Model, quantum gravity and gravitational waves.
- [Quantum Foundations](https://space-kitty.com/topics/quantum-foundations): Loophole-free Bell tests, the measurement problem, contextuality, Wigner's-friend scenarios and experimental tests of collapse models. (244 papers)
- [Quantum Many-Body Physics & Simulation](https://space-kitty.com/topics/many-body-quantum-simulation): Thermalization and its breakdown, many-body localization, quantum scars, discrete time crystals and analog quantum simulators. (219 papers)
- [Topological Phases & Anyons](https://space-kitty.com/topics/topological-matter): Topological insulators and semimetals, fractional Chern insulators, the fractional quantum anomalous Hall effect in moire materials and non-Abelian anyons. (249 papers)
- [Particle Physics & Beyond the Standard Model](https://space-kitty.com/topics/particle-physics-bsm): Higgs precision, the muon g-2 saga, neutrino masses and oscillations, flavor anomalies and collider searches for new physics. (231 papers)
- [Quantum Gravity & Holography](https://space-kitty.com/topics/quantum-gravity-holography): AdS/CFT, the black-hole information problem and islands, entanglement and the emergence of spacetime, and de Sitter quantum gravity. (248 papers)
- [Gravitational-Wave Astronomy](https://space-kitty.com/topics/gravitational-waves): LIGO-Virgo-KAGRA compact-binary catalogs, multimessenger neutron-star mergers, the nanohertz pulsar-timing background and tests of general relativity. (275 papers)

### Superconductivity & Quantum Materials
Mechanisms and materials of superconductivity: cuprates, nickelates, hydrides, moire systems, topological superconductors, applied HTS and computational discovery.
- [Cuprates & the Pairing Mechanism](https://space-kitty.com/topics/cuprate-mechanism): High-Tc cuprates, the Hubbard model and its numerics, the pseudogap, strange-metal transport, charge order and d-wave pairing. (235 papers)
- [Nickelate & Iron-Based Superconductors](https://space-kitty.com/topics/nickelates-iron-based): Infinite-layer and Ruddlesden-Popper nickelates (including La3Ni2O7 under pressure and ambient-pressure films) and iron pnictides and chalcogenides. (236 papers)
- [Superconducting Hydrides Under Pressure](https://space-kitty.com/topics/hydride-superconductors): H3S, LaH10 and ternary hydrides; diamond-anvil-cell measurement challenges, reproducibility disputes and the search for metastable low-pressure hydrides. (237 papers)
- [Room-Temperature Superconductivity Claims & Replication](https://space-kitty.com/topics/room-temperature-claims): High-profile claims (LK-99, retracted hydride papers) and replication efforts; the evidentiary standard of zero resistance plus a bulk Meissner effect. (232 papers)
- [Moire & 2D Superconductivity](https://space-kitty.com/topics/moire-superconductivity): Magic-angle graphene, twisted transition-metal dichalcogenides, rhombohedral multilayer graphene and chiral or unconventional 2D superconductivity. (245 papers)
- [Topological Superconductivity & Majorana Modes](https://space-kitty.com/topics/topological-superconductivity): Majorana zero modes in nanowires, Kitaev chains, vortex-bound states in iron-based materials and the reproducibility debate. (240 papers)
- [Applied Superconductivity & HTS Magnets](https://space-kitty.com/topics/applied-superconductivity): REBCO coated conductors, 20-tesla-class fusion magnets, MRI, power cables, superconducting RF cavities and superconducting electronics. (240 papers)
- [Computational & AI-Driven Superconductor Discovery](https://space-kitty.com/topics/superconductor-discovery): Ab initio Eliashberg predictions, machine-learning Tc models and high-throughput screening for new conventional and unconventional superconductors. (252 papers)

### Advanced Medicine
Clinical and translational frontiers: immunotherapy, mRNA and gene editing, gene and cell therapy, incretin drugs, neurodegeneration, aging, infectious disease, cardiovascular therapeutics and clinical AI.
- [Cancer Immunotherapy](https://space-kitty.com/topics/cancer-immunotherapy): Immune checkpoint inhibitors, CAR-T and TIL cell therapies including solid tumors, T-cell engagers and bispecifics, and antibody-drug conjugates. (288 papers)
- [mRNA Therapeutics & Cancer Vaccines](https://space-kitty.com/topics/mrna-cancer-vaccines): Personalized neoantigen mRNA vaccines, lipid-nanoparticle delivery, self-amplifying and circular RNA and mRNA therapeutics beyond infectious disease. (223 papers)
- [CRISPR & Gene-Editing Therapies](https://space-kitty.com/topics/gene-editing-therapies): Approved and investigational CRISPR-Cas9 therapies, base and prime editing, in vivo LNP-delivered editing and bespoke editing for ultra-rare disease. (264 papers)
- [Gene & Cell Therapy](https://space-kitty.com/topics/gene-cell-therapy): AAV and lentiviral gene therapy, in vivo CAR-T, iPSC- and stem-cell-derived replacement therapies such as islets and dopaminergic neurons. (232 papers)
- [GLP-1 & Incretin Therapies](https://space-kitty.com/topics/glp1-metabolic): Semaglutide, tirzepatide and next-generation incretin agonists; obesity, diabetes, cardiovascular, renal, liver and neuropsychiatric outcomes. (230 papers; dossier https://space-kitty.com/api/v1/dossiers/glp1-metabolic)
- [Alzheimer's, Parkinson's & Neurodegeneration](https://space-kitty.com/topics/neurodegeneration): Anti-amyloid antibodies, plasma p-tau biomarkers, alpha-synuclein seed amplification, antisense therapies for ALS and emerging disease-modifying strategies. (354 papers)
- [Biology of Aging & Longevity](https://space-kitty.com/topics/aging-longevity): Hallmarks of aging, senolytics, epigenetic clocks, partial reprogramming, mTOR and other geroprotective interventions. (305 papers)
- [Infectious Disease, Vaccines & Antimicrobial Resistance](https://space-kitty.com/topics/infectious-disease-amr): New antibiotic classes and AI-discovered antibiotics, phage therapy, long-acting HIV prevention and next-generation vaccines. (253 papers)
- [AI in Clinical Medicine](https://space-kitty.com/topics/ai-medicine): Validated diagnostic AI, medical large language models, AI-discovered drug candidates in clinical trials and evidence standards for clinical deployment. (254 papers)
- [Cardiovascular Therapeutics](https://space-kitty.com/topics/cardiovascular-innovation): Lipoprotein(a)-lowering drugs, siRNA and gene-editing approaches to LDL cholesterol, CETP inhibition and other cardiovascular advances. (252 papers)

### Biotechnology & Life Sciences
AI protein design, single-cell and spatial omics, synthetic biology and organoid systems.
- [AI Protein Design & Structure Prediction](https://space-kitty.com/topics/protein-design): AlphaFold and successors, diffusion-based protein design, inverse folding and de novo binders and enzymes. (323 papers)
- [Single-Cell & Spatial Omics](https://space-kitty.com/topics/single-cell-spatial): Single-cell atlases, spatial transcriptomics and proteomics, perturbation screens and foundation models of cells. (354 papers)
- [Synthetic Biology & Genome Engineering](https://space-kitty.com/topics/synthetic-biology): Synthetic genomes, genetic circuits, cell-free systems, genome writing and biomanufacturing, plus biosafety and governance considerations. (317 papers)
- [Organoids & Organ-on-Chip](https://space-kitty.com/topics/organoids): Brain and tissue organoids, assembloids, organ-on-chip platforms and their use in disease modeling and drug testing. (228 papers)

### Neuroscience & Brain-Computer Interfaces
Brain-computer interfaces, connectomics, NeuroAI and next-generation psychiatric therapeutics.
- [Brain-Computer Interfaces](https://space-kitty.com/topics/brain-computer-interfaces): Speech and handwriting neuroprostheses, high-channel-count intracortical arrays, endovascular and minimally invasive BCIs and closed-loop stimulation. (280 papers)
- [Connectomics & Brain Mapping](https://space-kitty.com/topics/connectomics): Whole-brain connectomes, cubic-millimeter cortical reconstructions, expansion microscopy and brain-wide cell atlases. (338 papers)
- [NeuroAI & Computational Neuroscience](https://space-kitty.com/topics/neuroai): Neural networks as models of the brain, predictive coding, neural population dynamics and foundation models trained on neural data. (227 papers)
- [Novel Psychiatric Therapeutics](https://space-kitty.com/topics/psychiatric-therapeutics): Psychedelic-assisted therapy, muscarinic antipsychotics, neurosteroids, rapid-acting antidepressants and accelerated neuromodulation. (359 papers)

### Fusion, Energy & Climate
Magnetic and inertial fusion, next-generation batteries and photovoltaics, AI weather and climate models, and carbon dioxide removal.
- [Magnetic Confinement Fusion](https://space-kitty.com/topics/magnetic-fusion): Tokamaks and stellarators, ITER, compact high-field devices, plasma confinement records and machine-learning plasma control. (246 papers)
- [Inertial Confinement Fusion](https://space-kitty.com/topics/inertial-fusion): Ignition and target gain at the National Ignition Facility, implosion physics and laser and pulsed-power drivers. (244 papers)
- [Next-Generation Batteries](https://space-kitty.com/topics/next-gen-batteries): Solid-state electrolytes, lithium-metal and silicon anodes, sodium-ion chemistries and machine-learning degradation prediction. (247 papers)
- [Perovskite & Tandem Photovoltaics](https://space-kitty.com/topics/advanced-photovoltaics): Perovskite solar-cell efficiency and stability, perovskite-silicon and all-perovskite tandems and scale-up. (249 papers)
- [AI Weather & Climate Modeling](https://space-kitty.com/topics/ai-weather-climate): Machine-learning weather prediction (GraphCast, GenCast, Aurora), hybrid climate models (NeuralGCM) and kilometer-scale simulation. (247 papers)
- [Carbon Dioxide Removal](https://space-kitty.com/topics/carbon-removal): Direct air capture sorbents and costs, enhanced rock weathering, ocean alkalinity enhancement and monitoring, reporting and verification. (97 papers)

### Materials & Nanotechnology
2D materials and heterostructures, semiconductor device frontiers, metamaterials and integrated photonics.
- [2D Materials & Van der Waals Heterostructures](https://space-kitty.com/topics/2d-materials): Graphene and transition-metal dichalcogenides, 2D magnets, moire excitons and van der Waals device engineering. (248 papers)
- [Semiconductor Device Frontiers](https://space-kitty.com/topics/semiconductor-frontiers): Gate-all-around and 2D-channel transistors, backside power delivery, advanced packaging and in-memory and neuromorphic hardware. (220 papers)
- [Metamaterials, Nanophotonics & Integrated Photonics](https://space-kitty.com/topics/metamaterials-photonics): Metasurfaces, thin-film lithium niobate, integrated photonic circuits and optical computing for AI. (239 papers)

### Astrophysics & Cosmology
Dark energy and cosmological tensions, JWST and the early universe, exoplanets and biosignatures, black holes and dark matter.
- [Dark Energy & Cosmological Tensions](https://space-kitty.com/topics/dark-energy-hubble-tension): DESI baryon acoustic oscillations and evolving dark energy hints, the Hubble tension, S8 and the status of Lambda-CDM. (233 papers)
- [JWST & the Early Universe](https://space-kitty.com/topics/early-universe-jwst): High-redshift galaxy discoveries, little red dots, early supermassive black holes and reionization as seen by JWST. (247 papers)
- [Exoplanets & Biosignatures](https://space-kitty.com/topics/exoplanets-biosignatures): JWST exoplanet atmospheres, temperate sub-Neptunes and rocky worlds, and the debate over claimed biosignature gases. (245 papers)
- [Black Holes & Event Horizon Imaging](https://space-kitty.com/topics/black-hole-physics): Event Horizon Telescope images of M87* and Sgr A*, polarization and spin measurements and black-hole ringdown tests. (238 papers)
- [Dark Matter Searches](https://space-kitty.com/topics/dark-matter): WIMP direct detection (LZ, XENONnT, PandaX), axion haloscopes, primordial black holes and astrophysical constraints. (253 papers)

### Mathematics & Theoretical Computer Science
AI for mathematics and formal proof, landmark results in pure mathematics, and algorithmic and complexity breakthroughs.
- [AI for Mathematics & Formal Proof](https://space-kitty.com/topics/ai-mathematics): Lean and Mathlib, autoformalization, neural theorem proving, olympiad-level systems and AI-assisted discovery in mathematics. (226 papers)
- [Landmark Results in Pure Mathematics](https://space-kitty.com/topics/landmark-math-results): Recent major theorems and their status: geometric Langlands, Kakeya in three dimensions, sphere packing, the unknotting-number additivity counterexample and more. (228 papers)
- [Algorithms & Complexity Breakthroughs](https://space-kitty.com/topics/algorithms-complexity): Almost-linear-time max flow, shortest paths beyond Dijkstra's sorting barrier, matrix multiplication exponent improvements and space-time simulation results. (192 papers)

## Endpoint reference

- GET https://space-kitty.com/api/v1 (free): API index: endpoints, pricing, payment terms, archive statistics.
- GET https://space-kitty.com/api/v1/domains (free): Research domains with topic and paper counts.
- GET https://space-kitty.com/api/v1/topics (free): All topics (filter with ?domain=). Params: domain.
- GET https://space-kitty.com/api/v1/topics/{slug} (free): Topic overview: description, dossier preview, top and newest papers.
- GET https://space-kitty.com/api/v1/topics/{slug}/papers (free): Ranked paper metadata for a topic, with abstracts where licensed. Params: sort=top|recent, limit (≤100), offset, kind.
- GET https://space-kitty.com/api/v1/search (free): Full-text search over papers, trials and dossiers with highlighted snippets. Params: q, type=all|papers|dossiers, topic, kind, year_from, year_to, limit (≤50), offset.
- GET https://space-kitty.com/api/v1/papers/{id} (free): One paper or trial record (ids like arxiv:2408.13687, doi:10.1038/…, nct:NCT05000000).
- GET https://space-kitty.com/api/v1/latest (free): Newest additions across all topics. Params: topic, limit (≤50).
- GET https://space-kitty.com/api/v1/dossiers (free): Dossier catalog with summaries, statistics and prices. Params: domain.
- GET https://space-kitty.com/api/v1/dossiers/{slug}/preview (free): Free dossier preview: summary, contents, statistics, verification record, sample claims.
- GET https://space-kitty.com/api/v1/dossiers/{slug} ($0.20): Full dossier: Markdown body, structured claims with citations, timeline, benchmarks, open problems, glossary, resolved bibliography. Send Accept: text/markdown for Markdown.
- GET https://space-kitty.com/api/v1/topics/{slug}/pack ($0.20): Research pack: the topic dossier plus the 50 most influential and 25 newest papers (with licensed abstracts) and related trials, in one JSON document.
- POST https://space-kitty.com/mcp (free): Model Context Protocol endpoint (Streamable HTTP, JSON responses). Free search tools; paid tools settle via x402.

## Content negotiation

- Send `Accept: text/markdown` (or add `?format=md`) to any page for a Markdown rendering.
- Paper ids: arxiv:<id>, doi:<doi>, pmc:<PMCID>, nct:<NCT id>, openalex:<W id>.

## Optional
- [About, sources & methodology](https://space-kitty.com/about)
- [Terms](https://space-kitty.com/terms)
- [Atom feed](https://space-kitty.com/feed.xml)