# Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes

Article · Domenica M. Rubino, Frank L. Greenway, Usman Khalid, Patrick M. O’Neil, Julio Rosenstock, Rasmus Sørrig, Thomas A. Wadden, Alicja Wizert, William Timothy Garvey, STEP 8 Investigators, Carlos Arauz-Pacheco, Kevin Cannon, H. Jackson Downey, David Fitz-Patrick, Jeffrey Geohas, Gregg Gerety, John Gilbert, Priscilla Hollander, Eric Klein, Karen Laufer, Philip O'Donnell, Paul Rosenblit, Phillip D. Toth

- Archive id: doi:10.1001/jama.2021.23619
- Published: 2022-01-11
- Venue: JAMA
- DOI: https://doi.org/10.1001/jama.2021.23619
- PMID: 35015037
- Citations: 994
- Source URL: https://doi.org/10.1001/jama.2021.23619
- PDF: https://jamanetwork.com/journals/jama/articlepdf/2787907/jama_rubino_2022_oi_210142_1641310203.77797.pdf
- Provenance: openalex

_Abstract not reproduced: its license does not permit redistribution. See the source URL._

Topics: [GLP-1 & Incretin Therapies](https://space-kitty.com/topics/glp1-metabolic)

Cited in dossiers:
- [GLP-1 & Incretin Therapies: State of the Field (October 2026)](https://space-kitty.com/dossiers/glp1-metabolic)

---
Space Kitty Archive · https://space-kitty.com · API: https://space-kitty.com/api/v1 · MCP: https://space-kitty.com/mcp · Premium: $0.20/request via x402 (Base Sepolia (testnet)). Metadata: arXiv (CC0), OpenAlex (CC0), Europe PMC (CC BY/CC0 works), ClinicalTrials.gov.