# Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide

Article · Jesper F. Lau, Paw Bloch, Lauge Schäffer, Ingrid Pettersson, Jane C. Spetzler, Jacob Kofoed, Kjeld Madsen, Lotte Bjerre Knudsen, James McGuire, Dorte B. Steensgaard, Holger M. Strauss, Dorte Xenia Gram, Sanne Møller Knudsen, Flemming Seier Nielsen, Peter Thygesen, Steffen Reedtz‐Runge, Thomas Kruse

- Archive id: doi:10.1021/acs.jmedchem.5b00726
- Published: 2015-08-26
- Venue: Journal of Medicinal Chemistry
- DOI: https://doi.org/10.1021/acs.jmedchem.5b00726
- PMID: 26308095
- Citations: 1,104
- Source URL: https://doi.org/10.1021/acs.jmedchem.5b00726
- Provenance: openalex

_Abstract not reproduced: its license does not permit redistribution. See the source URL._

Topics: [GLP-1 & Incretin Therapies](https://space-kitty.com/topics/glp1-metabolic)

Cited in dossiers:
- [GLP-1 & Incretin Therapies: State of the Field (October 2026)](https://space-kitty.com/dossiers/glp1-metabolic)

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