# Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells

Article · Olivier De Henau, Matthew P Rausch, David Alan Winkler, Luís Felipe Campesato, Cailian Liu, Daniel Hirschhorn-Cymerman, Sadna Budhu, Arnab Ghosh, Melissa M. Pink, Jeremy H. Tchaicha, Mark Douglas, Thomas T. Tibbitts, Sujata Pandit Sharma, Jennifer Proctor, Nicole Kosmider, Kerry White, Howard Marvin Stern, John R. Soglia, Julian Adams, Vito J. Palombella, Karen McGovern, Jeffery Lorne Kutok, Jedd D. Wolchok, Taha Merghoub

- Archive id: doi:10.1038/nature20554
- Published: 2016-11-01
- Venue: Nature
- DOI: https://doi.org/10.1038/nature20554
- PMID: 27828943
- Citations: 868
- Source URL: https://doi.org/10.1038/nature20554
- Provenance: openalex

_Abstract not reproduced: its license does not permit redistribution. See the source URL._

Topics: [Cancer Immunotherapy](https://space-kitty.com/topics/cancer-immunotherapy)

---
Space Kitty Archive · https://space-kitty.com · API: https://space-kitty.com/api/v1 · MCP: https://space-kitty.com/mcp · Premium: $0.20/request via x402 (Base Sepolia (testnet)). Metadata: arXiv (CC0), OpenAlex (CC0), Europe PMC (CC BY/CC0 works), ClinicalTrials.gov.