# IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies

Article · Christian Leborgne, Elena Barbon, Jeffrey M. Alexander, Hayley A. Hanby, Sandrine Delignat, Daniel M. Cohen, Fanny Collaud, Saghana Muraleetharan, Daniel Lupo, Joseph Silverberg, Karen Huang, Laetitia van Wittenberghe, Béatrice Marolleau, Adeline Miranda, Anna Fabiano, Victoria Daventure, Heena Beck, Xavier M. Anguela, Giuseppe Ronzitti, Sean M. Armour, Sébastien Lacroix‐Desmazes, Federico Mingozzi

- Archive id: doi:10.1038/s41591-020-0911-7
- Published: 2020-06-01
- Venue: Nature Medicine
- DOI: https://doi.org/10.1038/s41591-020-0911-7
- PMID: 32483358
- Citations: 335
- Source URL: https://doi.org/10.1038/s41591-020-0911-7
- Provenance: openalex

_Abstract not reproduced: its license does not permit redistribution. See the source URL._

Topics: [Gene & Cell Therapy](https://space-kitty.com/topics/gene-cell-therapy)

---
Space Kitty Archive · https://space-kitty.com · API: https://space-kitty.com/api/v1 · MCP: https://space-kitty.com/mcp · Premium: $0.20/request via x402 (Base Sepolia (testnet)). Metadata: arXiv (CC0), OpenAlex (CC0), Europe PMC (CC BY/CC0 works), ClinicalTrials.gov.