# AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset

Article · David Goertsen, Nicholas C. Flytzanis, Nick Goeden, Miguel R. Chuapoco, Alexander C. Cummins, Yijing Chen, Yingying Fan, Qiangge Zhang, Jitendra Sharma, Yangyang Duan, Liping Wang, Guoping Feng, Yu Chen, Nancy Y. Ip, James M. Pickel, Viviana Gradinaru

- Archive id: doi:10.1038/s41593-021-00969-4
- Published: 2021-12-09
- Venue: Nature Neuroscience
- DOI: https://doi.org/10.1038/s41593-021-00969-4
- PMID: 34887588
- Citations: 420
- Source URL: https://doi.org/10.1038/s41593-021-00969-4
- PDF: https://www.biorxiv.org/content/biorxiv/early/2020/06/17/2020.06.16.152975.full.pdf
- Provenance: openalex

_Abstract not reproduced: its license does not permit redistribution. See the source URL._

Topics: [Gene & Cell Therapy](https://space-kitty.com/topics/gene-cell-therapy)

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