# Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting PCSK9 in Nonhuman Primate and Mouse Models

Article · Richard G. Lee, Anne Marie Mazzola, Maurine C. Braun, Colin Platt, Scott B. Vafai, Sekar Kathiresan, Ellen Rohde, Andrew M. Bellinger, Amit V. Khera

- Archive id: doi:10.1161/circulationaha.122.062132
- Published: 2022-10-31
- Venue: Circulation
- DOI: https://doi.org/10.1161/circulationaha.122.062132
- PMID: 36314243
- Citations: 243
- Source URL: https://doi.org/10.1161/circulationaha.122.062132
- Provenance: openalex

_Abstract not reproduced: its license does not permit redistribution. See the source URL._

Topics: [CRISPR & Gene-Editing Therapies](https://space-kitty.com/topics/gene-editing-therapies)

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