# Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT)

Clinical trial · Seattle Institute for Biomedical and Clinical Research

- Archive id: nct:NCT00007189
- Published: 2000-12-14
- Venue: ClinicalTrials.gov
- ClinicalTrials.gov: https://clinicaltrials.gov/study/NCT00007189
- Source URL: https://clinicaltrials.gov/study/NCT00007189
- Provenance: clinicaltrials

## Abstract

The purpose of this trial is to test the ability of the non-steroidal anti-inflammatory medications naproxen and celecoxib to delay or prevent the onset of AD and age-related cognitive decline.

_Abstract reproduced under ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters._

## Trial details

- status: COMPLETED
- phase: PHASE3
- study type: INTERVENTIONAL
- enrollment: 2625
- sponsor: Seattle Institute for Biomedical and Clinical Research
- conditions: Alzheimer Disease
- interventions: DRUG: Naproxen Sodium (Aleve); DRUG: Celecoxib (Celebrex)
- start date: 2001-01-01
- primary completion date: 2007-05-01
- has results: false
- data source: ClinicalTrials.gov
- data processed: 2026-10-29T09:00:05
- modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Topics: [Alzheimer's, Parkinson's & Neurodegeneration](https://space-kitty.com/topics/neurodegeneration)

---
Space Kitty Archive · https://space-kitty.com · API: https://space-kitty.com/api/v1 · MCP: https://space-kitty.com/mcp · Premium: $0.20/request via x402 (Base Sepolia (testnet)). Metadata: arXiv (CC0), OpenAlex (CC0), Europe PMC (CC BY/CC0 works), ClinicalTrials.gov.