# Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission

Clinical trial · National Institute of Allergy and Infectious Diseases (NIAID)

- Archive id: nct:NCT00021671
- Published: 2001-08-31
- Venue: ClinicalTrials.gov
- ClinicalTrials.gov: https://clinicaltrials.gov/study/NCT00021671
- Source URL: https://clinicaltrials.gov/study/NCT00021671
- Provenance: clinicaltrials

## Abstract

The purpose of this study is to see if antibiotic drugs given to treat an infection of the uterus during pregnancy can reduce the chances of HIV being passed from an HIV-positive mother to her baby. A link between bacterial disease of the vagina, premature birth, infection of the uterus during pregnancy, and the passing of HIV from a mother to her baby has been found. Early treatment of these problems may reduce the risk of passing HIV from an HIV-positive mother to her baby. \\\[Note: As of 02/21/03, enrollment into this study was halted because preliminary data showed that the study antibiotics were not effective in preventing mother-to-child HIV transmission.\\\]

_Abstract reproduced under ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters._

## Trial details

- status: COMPLETED
- phase: PHASE3
- study type: INTERVENTIONAL
- enrollment: 3720
- sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- conditions: HIV Infections
- interventions: DRUG: Erythromycin; DRUG: Nevirapine; DRUG: Ampicillin sodium; DRUG: Metronidazole
- has results: false
- data source: ClinicalTrials.gov
- data processed: 2026-10-29T09:00:05
- modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Topics: [Infectious Disease, Vaccines & Antimicrobial Resistance](https://space-kitty.com/topics/infectious-disease-amr)

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