# Simplified Selective Digestive Tract Decontamination for the Prevention of Intensive Care Unit Acquired Infections

Clinical trial · Rambam Health Care Campus

- Archive id: nct:NCT01798537
- Published: 2013-02-26
- Venue: ClinicalTrials.gov
- ClinicalTrials.gov: https://clinicaltrials.gov/study/NCT01798537
- Source URL: https://clinicaltrials.gov/study/NCT01798537
- Provenance: clinicaltrials

## Abstract

A simplified graded gut decontamination protocol combined with rigorous bi-weekly screening and appropriate bacterial prophylaxis, will lead to a 25% reduction in the acquisition of blood stream infections and to a 25% reduction in lower airway colonization with multi drug resistant organisms. There will be no concomitant rise in gram-positive or fungal infection or a surgency of new resistance patterns.

_Abstract reproduced under ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters._

## Trial details

- acronym: SDDICU
- status: UNKNOWN
- phase: PHASE2, PHASE3
- study type: INTERVENTIONAL
- enrollment: 2400
- sponsor: Rambam Health Care Campus
- conditions: Bacteremia Associated With Intravascular Line; Ventilator Associated Pneumonia; Bacteremia
- interventions: DRUG: Neomycin Colistin Nystatin Vancomycin
- start date: 2013-06-01
- primary completion date: 2015-07-01
- has results: false
- data source: ClinicalTrials.gov
- data processed: 2026-10-29T09:00:05
- modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Topics: [Infectious Disease, Vaccines & Antimicrobial Resistance](https://space-kitty.com/topics/infectious-disease-amr)

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