# Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Clinical trial · UMC Utrecht

- Archive id: nct:NCT02735707
- Published: 2016-04-13
- Venue: ClinicalTrials.gov
- ClinicalTrials.gov: https://clinicaltrials.gov/study/NCT02735707
- Source URL: https://clinicaltrials.gov/study/NCT02735707
- Provenance: clinicaltrials

## Abstract

REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of patients admitted to intensive care with community-acquired pneumonia. In addition, REMAP-CAP provides and adaptive research platform for evaluation of multiple treatment modalities in the event of a respiratory pandemic such as COVID-19. REMAP-COVID is a sub-platform of REMAP-CAP that evaluates treatments specific to COVID-19 in the United States of America.

_Abstract reproduced under ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters._

## Trial details

- acronym: REMAP-CAP
- status: RECRUITING
- phase: PHASE3
- study type: INTERVENTIONAL
- enrollment: 20000
- sponsor: UMC Utrecht
- conditions: Community-acquired Pneumonia, Influenza, COVID-19
- interventions: DRUG: Ceftriaxone; DRUG: Moxifloxacin or Levofloxacin; DRUG: Piperacillin-tazobactam; DRUG: Ceftaroline; DRUG: Amoxicillin-clavulanate; DRUG: Standard course macrolide; DRUG: Extended course macrolide; OTHER: No systemic corticosteroid; DRUG: Fixed-duration Hydrocortisone; DRUG: Shock-dependent hydrocortisone
- start date: 2016-04-11
- start date type: ACTUAL
- primary completion date: 2026-02-01
- has results: false
- data source: ClinicalTrials.gov
- data processed: 2026-10-29T09:00:05
- modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Topics: [Infectious Disease, Vaccines & Antimicrobial Resistance](https://space-kitty.com/topics/infectious-disease-amr)

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