# A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Participants With Early Alzheimer's Disease

Clinical trial · Eisai Co., Ltd.

- Archive id: nct:NCT02956486
- Published: 2016-11-07
- Venue: ClinicalTrials.gov
- ClinicalTrials.gov: https://clinicaltrials.gov/study/NCT02956486
- Source URL: https://clinicaltrials.gov/study/NCT02956486
- Provenance: clinicaltrials

## Abstract

The name of this trial is MissionAD1. This phase 3 study consists of a Core and Open Label Extension (OLE) Phase in participants with Early Alzheimer's Disease (EAD), and will be conducted to evaluate the efficacy and safety of E2609. The Core is a 24-month treatment, multicenter, double blind, placebo controlled parallel group study. The OLE is a 24-month treatment, one group study. The data for the studies E2609-G000-301 (NCT02956486, MissionAD1) and E2609-G000-302 (NCT03036280, MissionAD2) will be pooled.

_Abstract reproduced under ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters._

## Trial details

- acronym: MissionAD1
- status: TERMINATED
- phase: PHASE3
- study type: INTERVENTIONAL
- enrollment: 2212
- sponsor: Eisai Co., Ltd.
- conditions: Alzheimer's Disease
- interventions: DRUG: Elenbecestat; DRUG: Placebo
- start date: 2016-10-20
- start date type: ACTUAL
- primary completion date: 2020-01-15
- has results: true
- data source: ClinicalTrials.gov
- data processed: 2026-10-29T09:00:05
- modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Topics: [Alzheimer's, Parkinson's & Neurodegeneration](https://space-kitty.com/topics/neurodegeneration)

Cited in dossiers:
- [Alzheimer's, Parkinson's & Neurodegeneration: State of the Field (October 2026)](https://space-kitty.com/dossiers/neurodegeneration)

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