# ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions

Clinical trial · University of Birmingham

- Archive id: nct:NCT03838575
- Published: 2019-02-12
- Venue: ClinicalTrials.gov
- ClinicalTrials.gov: https://clinicaltrials.gov/study/NCT03838575
- Source URL: https://clinicaltrials.gov/study/NCT03838575
- Provenance: clinicaltrials

## Abstract

ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre interventions, used alone or in combination, to reduce SSI rates in patients undergoing surgery.

_Abstract reproduced under ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters._

## Trial details

- acronym: ROSSINI 2
- status: UNKNOWN
- phase: PHASE3
- study type: INTERVENTIONAL
- enrollment: 6610
- sponsor: University of Birmingham
- conditions: Surgical Site Infection; Surgical Wound Infection; Surgery--Complications; Surgery
- interventions: DRUG: 2% alcoholic chlorhexidine skin prep (SKIN PREP); DEVICE: Iodophor Antimicrobial Incise Drapes (DRAPE); DEVICE: Gentamicin-impregnated implants/ sponges (SPONGE); OTHER: NONE (Control)
- start date: 2019-03-01
- start date type: ACTUAL
- primary completion date: 2023-05-01
- has results: false
- data source: ClinicalTrials.gov
- data processed: 2026-10-29T09:00:05
- modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Topics: [Infectious Disease, Vaccines & Antimicrobial Resistance](https://space-kitty.com/topics/infectious-disease-amr)

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