# Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)

Clinical trial · Cybin IRL Limited

- Archive id: nct:NCT06605105
- Published: 2024-09-20
- Venue: ClinicalTrials.gov
- ClinicalTrials.gov: https://clinicaltrials.gov/study/NCT06605105
- Source URL: https://clinicaltrials.gov/study/NCT06605105
- Provenance: clinicaltrials

## Abstract

This is a long- term extension of the double-blind trials APPROACH (CYB003-002) and EMBRACE (CYB003-003). Its aim is to examine the safety and long-term efficacy of CYB003 in participants with MDD.

_Abstract reproduced under ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters._

## Trial details

- acronym: EXTEND
- status: ENROLLING_BY_INVITATION
- phase: PHASE3
- study type: INTERVENTIONAL
- enrollment: 468
- sponsor: Cybin IRL Limited
- conditions: Major Depressive Disorder
- interventions: DRUG: CYB003
- start date: 2025-07-18
- start date type: ACTUAL
- primary completion date: 2028-06-06
- has results: false
- data source: ClinicalTrials.gov
- data processed: 2026-10-29T09:00:05
- modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Topics: [Novel Psychiatric Therapeutics](https://space-kitty.com/topics/psychiatric-therapeutics)

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