# A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents

Clinical trial · Karuna Therapeutics, Inc., a Bristol Myers Squibb company

- Archive id: nct:NCT07424404
- Published: 2026-02-20
- Venue: ClinicalTrials.gov
- ClinicalTrials.gov: https://clinicaltrials.gov/study/NCT07424404
- Source URL: https://clinicaltrials.gov/study/NCT07424404
- Provenance: clinicaltrials

## Abstract

The purpose of this study is to evaluate the long-term safety and tolerability of Xanomeline and Trospium Chloride for the treatment of psychiatric disorders in children and adolescents

_Abstract reproduced under ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters._

## Trial details

- status: RECRUITING
- phase: PHASE3
- study type: INTERVENTIONAL
- enrollment: 400
- sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- conditions: Schizophrenia; Autism-Related Irritability
- interventions: DRUG: KarXT; DRUG: KarX-EC
- start date: 2026-04-07
- start date type: ACTUAL
- primary completion date: 2030-03-08
- has results: false
- data source: ClinicalTrials.gov
- data processed: 2026-10-29T09:00:05
- modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Topics: [Novel Psychiatric Therapeutics](https://space-kitty.com/topics/psychiatric-therapeutics)

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