# MDMA-AT for PTSD in Young Adults With Childhood Trauma

Clinical trial · Jenna M. Traynor

- Archive id: nct:NCT07765693
- Published: 2026-08-14
- Venue: ClinicalTrials.gov
- ClinicalTrials.gov: https://clinicaltrials.gov/study/NCT07765693
- Source URL: https://clinicaltrials.gov/study/NCT07765693
- Provenance: clinicaltrials

## Abstract

This study is testing a new, emerging treatment for young adults (ages 18-26) with Posttraumatic Stress Disorder (PTSD). The treatment is combining the substance, MDMA, with up to three psychotherapy sessions, also known as MDMA-Assisted Therapy (MDMA-AT). The main questions it aims to answer are: \* Is the treatment safe and feasible to administer? \* Does the treatment improve PTSD symptoms? Participants will be asked to: \* Complete screening procedures, including a medical and psychiatric evaluation to ensure safe participation \* Attend up to three preparatory talk therapy sessions prior to the first MDMA-AT dosing session \* Attend three integration talk therapy sessions after each MDMA-AT dosing session \* Attend up to three total MDMA-AT dosing sessions \* Complete assessments from baseline to 38-weeks post-baseline \* Complete a fMRI scan at baseline and at 18-weeks post-treatment \* Complete self-report measures and ecological momentary assessments (EMAs) across the study period

_Abstract reproduced under ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters._

## Trial details

- status: NOT_YET_RECRUITING
- phase: PHASE2
- study type: INTERVENTIONAL
- enrollment: 15
- sponsor: Jenna M. Traynor
- conditions: Posttraumatic Stress Disorder (PTSD)
- interventions: DRUG: MDMA assisted psychotherapy
- start date: 2026-10-31
- start date type: ESTIMATED
- primary completion date: 2028-01-30
- has results: false
- data source: ClinicalTrials.gov
- data processed: 2026-10-29T09:00:05
- modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Topics: [Novel Psychiatric Therapeutics](https://space-kitty.com/topics/psychiatric-therapeutics)

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