The AlphaFold Database of Protein Structures: A Biologist's Guide

Abstract

AlphaFold, the deep learning algorithm developed by DeepMind, recently released the three-dimensional models of the whole human proteome to the scientific community. Here we discuss the advantages, limitations and the still unsolved challenges of the AlphaFold models from the perspective of a biologist, who may not be an expert in structural biology.

Abstract of "The AlphaFold Database of Protein Structures: A Biologist's Guide" by David A, Islam S, Tankhilevich E et al., https://doi.org/10.1016/j.jmb.2021.167336, used under its Creative Commons Attribution license (CC-BY); markup removed, otherwise unmodified.