AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset
David Goertsen, Nicholas C. Flytzanis, Nick Goeden, Miguel R. Chuapoco, Alexander C. Cummins, Yijing Chen, Yingying Fan, Qiangge Zhang, Jitendra Sharma, Yangyang Duan, Liping Wang, Guoping Feng, Yu Chen, Nancy Y. Ip, James M. Pickel, Viviana Gradinaru
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Record
- Archive ID
- doi:10.1038/s41593-021-00969-4
- Published
- Dec 9, 2021
- Venue
- Nature Neuroscience
- DOI
- 10.1038/s41593-021-00969-4
- PubMed
- 34887588
- Categories
- Virus-based gene therapy research
- Provenance
- openalex