CD19/22 Bi-specific CAR-T Cell Therapy

Shenzhen Geno-Immune Medical Institute

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Brief summary

The purpose of this study is to assess the feasibility, safety and efficacy of anti-CD19/22 bi-specific CAR-T cell therapy in patients with CD19 and/or CD22 positive B cell malignancies. Another goal of the study is to learn more about the safety and function of the anti-CD19/22 bi-specific CAR-T cells and their persistency in patients.

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Trial details

status
NOT_YET_RECRUITING
phase
PHASE1, PHASE2
study type
INTERVENTIONAL
enrollment
60
sponsor
Shenzhen Geno-Immune Medical Institute
conditions
B Cell Malignancies
interventions
BIOLOGICAL: bi-4SCAR CD19/22 T cells
start date
2027-06-01
start date type
ESTIMATED
primary completion date
2029-12-31
has results
false
data source
ClinicalTrials.gov
data processed
2026-10-29T09:00:05
modifications
selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Record

Archive ID
nct:NCT05432882
Published
Jun 27, 2022
Updated
Aug 26, 2026
Venue
ClinicalTrials.gov
ClinicalTrials.gov
NCT05432882
Categories
B Cell Malignancies
License
ClinicalTrials.gov terms (attribution, processing date, modifications noted)
Provenance
clinicaltrials

Topics