A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes

Eli Lilly and Company

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Brief summary

This study will investigate the safety and efficacy of once daily oral treatment with orforglipron compared with placebo on body weight in adult participants with obesity or overweight and type 2 diabetes. The study will last about 77 weeks and may include up to 22 visits.

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Trial details

acronym
ATTAIN-2
status
COMPLETED
phase
PHASE3
study type
INTERVENTIONAL
enrollment
1613
sponsor
Eli Lilly and Company
conditions
Obesity; Overweight; Type 2 Diabetes
interventions
DRUG: Orforglipron; DRUG: Placebo
start date
2023-06-05
start date type
ACTUAL
primary completion date
2025-08-08
has results
true
data source
ClinicalTrials.gov
data processed
2026-10-29T09:00:05
modifications
selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Record

Archive ID
nct:NCT05872620
Published
May 24, 2023
Updated
Sep 4, 2026
Venue
ClinicalTrials.gov
ClinicalTrials.gov
NCT05872620
Categories
Obesity, Overweight, Type 2 Diabetes
License
ClinicalTrials.gov terms (attribution, processing date, modifications noted)
Provenance
clinicaltrials

Topics

Cited in dossiers