A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease

Eli Lilly and Company

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Brief summary

The main purpose of this study is to evaluate the efficacy and safety of retatrutide once weekly in participants with obesity and established cardiovascular disease (CVD). The study will last about 113 weeks.

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Trial details

acronym
TRIUMPH-3
status
COMPLETED
phase
PHASE3
study type
INTERVENTIONAL
enrollment
1946
sponsor
Eli Lilly and Company
conditions
Obesity; Cardiovascular Diseases
interventions
DRUG: Retatrutide; DRUG: Placebo
start date
2023-05-30
start date type
ACTUAL
primary completion date
2026-04-16
has results
false
data source
ClinicalTrials.gov
data processed
2026-10-29T09:00:05
modifications
selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Record

Archive ID
nct:NCT05882045
Published
May 31, 2023
Updated
Jul 30, 2026
Venue
ClinicalTrials.gov
ClinicalTrials.gov
NCT05882045
Categories
Obesity, Cardiovascular Diseases
License
ClinicalTrials.gov terms (attribution, processing date, modifications noted)
Provenance
clinicaltrials

Topics

Cited in dossiers