A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

AstraZeneca

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Brief summary

This is a global, randomised, Phase III, multicentre, open-label study evaluating the efficacy, safety and the degree of added benefit of the Surovatamig (AZD0486) plus rituximab combination compared to Investigator's choice of 3 standard immunochemotherapy regimen, conducted in participants with untreated FL.

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Trial details

status
RECRUITING
phase
PHASE3
study type
INTERVENTIONAL
enrollment
1018
sponsor
AstraZeneca
conditions
Untreated Follicular Lymphoma
interventions
DRUG: Surovatamig; DRUG: R-CHOP; DRUG: R-CVP; DRUG: BR
start date
2024-08-07
start date type
ACTUAL
primary completion date
2031-11-26
has results
false
data source
ClinicalTrials.gov
data processed
2026-10-29T09:00:05
modifications
selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Record

Archive ID
nct:NCT06549595
Published
Aug 12, 2024
Updated
Oct 21, 2026
Venue
ClinicalTrials.gov
ClinicalTrials.gov
NCT06549595
Categories
Untreated Follicular Lymphoma
License
ClinicalTrials.gov terms (attribution, processing date, modifications noted)
Provenance
clinicaltrials

Topics