Evaluating the Efficacy and Safety of LUM-201 Plus Semaglutide Versus Semaglutide Plus Placebo in Older Obese Adults

Lumos Pharma

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Brief summary

This is a phase 2 randomized, double-blind, placebo-controlled, multi-center study evaluating the efficacy and safety of LUM-201 plus Semaglutide versus Semaglutide plus placebo in obese adults with body mass index between 30 and 45 kg/m\^2, between the ages of 60 and 85 years that have mild functional impairment.

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Trial details

status
NOT_YET_RECRUITING
phase
PHASE2
study type
INTERVENTIONAL
enrollment
202
sponsor
Lumos Pharma
conditions
Obesity & Overweight
interventions
DRUG: LUM-201; DRUG: Placebo; DRUG: Semagludtide
start date
2027-02-15
start date type
ESTIMATED
primary completion date
2028-02-15
has results
false
data source
ClinicalTrials.gov
data processed
2026-10-29T09:00:05
modifications
selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Record

Archive ID
nct:NCT07754045
Published
Aug 10, 2026
Venue
ClinicalTrials.gov
ClinicalTrials.gov
NCT07754045
Categories
Obesity & Overweight
License
ClinicalTrials.gov terms (attribution, processing date, modifications noted)
Provenance
clinicaltrials

Topics