Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes

Amgen

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Brief summary

The main objective of this trial is to evaluate whether maridebart cafraglutide is non-inferior to semaglutide in improving glycemic control in participants with type 2 diabetes (T2D) who are receiving metformin treatment, with or without a sodium-glucose cotransporter-2 (SGLT-2) inhibitor.

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Trial details

acronym
MARITIME-T2D-3
status
NOT_YET_RECRUITING
phase
PHASE3
study type
INTERVENTIONAL
enrollment
1300
sponsor
Amgen
conditions
Diabetes Mellitus, Type 2
interventions
DRUG: Maridebart cafraglutide; DRUG: Semaglutide
start date
2026-11-02
start date type
ESTIMATED
primary completion date
2028-09-04
has results
false
data source
ClinicalTrials.gov
data processed
2026-10-29T09:00:05
modifications
selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Record

Archive ID
nct:NCT07866066
Published
Oct 8, 2026
Venue
ClinicalTrials.gov
ClinicalTrials.gov
NCT07866066
Categories
Diabetes Mellitus, Type 2
License
ClinicalTrials.gov terms (attribution, processing date, modifications noted)
Provenance
clinicaltrials

Topics