A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes

Eli Lilly and Company

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Brief summary

The purpose of this study is to investigate the efficacy and safety of eloralintide and tirzepatide coformulation (EloraTZP) compared with tirzepatide, eloralintide and placebo for body weight reduction in participants with obesity. Participation in the study will last about 2 years.

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Trial details

acronym
AMPLIFY-1
status
NOT_YET_RECRUITING
phase
PHASE3
study type
INTERVENTIONAL
enrollment
2115
sponsor
Eli Lilly and Company
conditions
Obesity
interventions
DRUG: eloralintide and tirzepatide; DRUG: Eloralintide; DRUG: Tirzepatide; DRUG: Placebo
start date
2026-12-01
start date type
ESTIMATED
primary completion date
2029-10-01
has results
false
data source
ClinicalTrials.gov
data processed
2026-10-29T09:00:05
modifications
selected fields only; whitespace normalized; brief summary truncated to 2,000 characters

Record

Archive ID
nct:NCT07881432
Published
Oct 19, 2026
Venue
ClinicalTrials.gov
ClinicalTrials.gov
NCT07881432
Categories
Obesity
License
ClinicalTrials.gov terms (attribution, processing date, modifications noted)
Provenance
clinicaltrials

Topics

Cited in dossiers