WHO global research priorities for antimicrobial resistance in human health

Silvia Bertagnolio, Zlatina Dobreva, Chad M. Centner, Ioana Diana Olaru, Daniele Donà, Stefano Burzo, Benedikt David Huttner, Antoine Chaillon, Nebiat G. Gebreselassie, Teodora Wi, Mateusz Hasso-Agopsowicz, Benedetta Allegranzi, Hatim F. Sati, Verica Ivanovska, Kavita U. Kothari, Hanan H. Balkhy, Alessandro Cassini, Raph L Hamers, Kitty Van Weezenbeek, David Aanensen, Alexandre Alanio, Ana Alastruey-Izquierdo, Tinsae Alemayehu, Majdi N. Al‐Hasan, Karel Allegaert, and 75 more

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Abstract

The WHO research agenda for antimicrobial resistance (AMR) in human health has identified 40 research priorities to be addressed by the year 2030. These priorities focus on bacterial and fungal pathogens of crucial importance in addressing AMR, including drug-resistant pathogens causing tuberculosis. These research priorities encompass the entire people-centred journey, covering prevention, diagnosis, and treatment of antimicrobial-resistant infections, in addition to addressing the overarching knowledge gaps in AMR epidemiology, burden and drivers, policies and regulations, and awareness and education. The research priorities were identified through a multistage process, starting with a comprehensive scoping review of knowledge gaps, with expert inputs gathered through a survey and open call. The priority setting involved a rigorous modified Child Health and Nutrition Research Initiative approach, ensuring global representation and applicability of the findings. The ultimate goal of this research agenda is to encourage research and investment in the generation of evidence to better understand AMR dynamics and facilitate policy translation for reducing the burden and consequences of AMR.

Abstract of "WHO global research priorities for antimicrobial resistance in human health" by Silvia Bertagnolio, Zlatina Dobreva, Chad M. Centner et al., https://doi.org/10.1016/s2666-5247(24)00134-4, used under its Creative Commons Attribution license (CC-BY); markup removed, otherwise unmodified.

Record

Archive ID
doi:10.1016/s2666-5247(24)00134-4
Published
Aug 13, 2024
Venue
The Lancet Microbe
DOI
10.1016/s2666-5247(24)00134-4
PubMed
39146948
Categories
Antibiotic Use and Resistance
License
cc-by
Provenance
openalex

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