Simplified Selective Digestive Tract Decontamination for the Prevention of Intensive Care Unit Acquired Infections

Brief summary

A simplified graded gut decontamination protocol combined with rigorous bi-weekly screening and appropriate bacterial prophylaxis, will lead to a 25% reduction in the acquisition of blood stream infections and to a 25% reduction in lower airway colonization with multi drug resistant organisms. There will be no concomitant rise in gram-positive or fungal infection or a surgency of new resistance patterns.

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Trial details

acronym

SDDICU

status

UNKNOWN

phase

PHASE2, PHASE3

study type

INTERVENTIONAL

enrollment

2400

sponsor

Rambam Health Care Campus

conditions

Bacteremia Associated With Intravascular Line; Ventilator Associated Pneumonia; Bacteremia

interventions

DRUG: Neomycin Colistin Nystatin Vancomycin

start date

2013-06-01

primary completion date

2015-07-01

has results

false

data source

ClinicalTrials.gov

data processed

2026-10-29T09:00:05

modifications

selected fields only; whitespace normalized; brief summary truncated to 2,000 characters