ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions

Brief summary

ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre interventions, used alone or in combination, to reduce SSI rates in patients undergoing surgery.

Source: ClinicalTrials.gov (U.S. National Library of Medicine), data processed 2026-10-29T09:00:05; modifications: selected fields only; whitespace normalized; brief summary truncated to 2,000 characters. Not a U.S. Government endorsement.

Trial details

acronym

ROSSINI 2

status

UNKNOWN

phase

PHASE3

study type

INTERVENTIONAL

enrollment

6610

sponsor

University of Birmingham

conditions

Surgical Site Infection; Surgical Wound Infection; Surgery--Complications; Surgery

interventions

DRUG: 2% alcoholic chlorhexidine skin prep (SKIN PREP); DEVICE: Iodophor Antimicrobial Incise Drapes (DRAPE); DEVICE: Gentamicin-impregnated implants/ sponges (SPONGE); OTHER: NONE (Control)

start date

2019-03-01

start date type

ACTUAL

primary completion date

2023-05-01

has results

false

data source

ClinicalTrials.gov

data processed

2026-10-29T09:00:05

modifications

selected fields only; whitespace normalized; brief summary truncated to 2,000 characters